2-Pyridylethylamine (hydrochloride)

2-Pyridylethylamine is a histamine-1 (H1R) receptor agonist. 2-Pyridylethylamine can reduce the joint injury induced by formalin in rats. 2-Pyridylethylamine can be used to study the spinal cord release of neuropeptide (NPY) [1].

Product Specifications

CAS Number

[3343-39-3]

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/2-pyridylethylamine-hydrochloride.html

Purity

99.86

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

NCCC1=CC=CC=N1.Cl.Cl

Molecular Formula

C7H12Cl2N2

Molecular Weight

195.09

Precautions

H315, H319, H320

References & Citations

[1]Souza-Silva E, et al. Intra-articular injection of 2-pyridylethylamine produces spinal NPY-mediated antinociception in the formalin-induced rat knee-joint pain model. Brain Res. 2020 May 15;1735:146757.