DDX58 Rabbit Monoclonal Antibody
Anti-DDX58 Monoclonal Antibody. Tested in WB, IP applications. This antibody reacts with Human.
Product Specifications
Product Name Alternative
Histone H2AX; H2a/x; Histone H2A.X; H2AFX; H2AX
UniProt
O95786
Reactivity
Human
Immunogen
A synthesized peptide derived from human DDX58 Retinoic acid inducible gene I (RIG-I) is a 925 amino acid, interferon-inducible cellular DExD/H box RNA helicase that activates type I interferon (IFN), an important effector of the innate immune system that is sensitive to these dsRNA viruses. dsRNA is normally present in very low quantities in cells, so when a virus is present, the elevated levels of dsRNA act as a sign telling RIG-I to activate the production of IFN.
Target
Antiviral innate immune response receptor RIG-I
Clonality
Monoclonal
Clone
BCEGCX6
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin, Immunology & Inflammation, Infectious Disease & Virology, Molecular Biology
Purification
Affinity-chromatography
Concentration
0.5mg/ml
Dilution
WB 1:500-2000 IP 1:50
Form
Liquid
Molecular Weight
100-110 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IP, WB
Host or Source
Rabbit
Preservative
Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.
Isotype
Rabbit IgG
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