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DDX58 Rabbit Monoclonal Antibody

Anti-DDX58 Monoclonal Antibody. Tested in WB, IP applications. This antibody reacts with Human.

Product Specifications

Product Name Alternative

Histone H2AX; H2a/x; Histone H2A.X; H2AFX; H2AX

UniProt

O95786

Reactivity

Human

Immunogen

A synthesized peptide derived from human DDX58 Retinoic acid inducible gene I (RIG-I) is a 925 amino acid, interferon-inducible cellular DExD/H box RNA helicase that activates type I interferon (IFN), an important effector of the innate immune system that is sensitive to these dsRNA viruses. dsRNA is normally present in very low quantities in cells, so when a virus is present, the elevated levels of dsRNA act as a sign telling RIG-I to activate the production of IFN.

Target

Antiviral innate immune response receptor RIG-I

Clonality

Monoclonal

Clone

BCEGCX6

Conjugation

Unconjugated

Field of Research

Epigenetics & Chromatin, Immunology & Inflammation, Infectious Disease & Virology, Molecular Biology

Purification

Affinity-chromatography

Concentration

0.5mg/ml

Dilution

WB 1:500-2000 IP 1:50

Form

Liquid

Molecular Weight

100-110 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

IP, WB

Host or Source

Rabbit

Preservative

Rabbit IgG in stabilizing components, phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. *This antibody is supplied in a stabilized formulation. Compatibility with conjugation reactions depends on the chemistry of the conjugation method used. For conjugation methods that are not compatible with the stabilizing components present in this formulation, a carrier-free antibody format is required.

Isotype

Rabbit IgG

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