PR5-LL-CM01
PR5-LL-CM01 is a potent protein arginine methyltransferase 5 (PRMT5) inhibitor (IC50= 7.5 μM) . Anti-tumor activies[1].
Product Specifications
CAS Number
[1005307-86-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pr5-ll-cm01.html
Purity
98.37
Solubility
DMSO : 11.11 mg/mL (ultrasonic; warming; adjust pH to 3 with HCl; heat to 80°C)
Smiles
CC1=CC=C(NC2=C3C(N(C4=CC=CC=C4)N=C3)=NC(NCCN(C)C)=N2)C=C1C
Molecular Formula
C23H27N7
Molecular Weight
401.51
Precautions
H302, H315, H319
References & Citations
[1]Prabhu L, et al. Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers. Oncotarget. 2017;8 (25) :39963-39977.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PRMT5
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
