Butenafine (Hydrochloride)

Butenafine Hydrochloride (KP363 Hydrochloride) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.

Product Specifications

CAS Number

[101827-46-7]

Product Name Alternative

KP363 (Hydrochloride)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Butenafine-Hydrochloride.html

Purity

99.95

Solubility

DMSO : 25 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic)

Smiles

CN(CC1=CC=C(C(C)(C)C)C=C1)CC2=C3C=CC=CC3=CC=C2.[H]Cl

Molecular Formula

C23H28ClN

Molecular Weight

353.93

Precautions

H302, H315, H319, H335

References & Citations

[1]Singal A. Butenafine and superficial mycoses: current status. Expert Opin Drug Metab Toxicol. 2008 Jul;4 (7) :999-1005.|[2]Kokjohn K, Bradley M, Griffiths B, Ghannoum M. Evaluation of in vitro activity of ciclopirox olamine, butenafine HCl and econazole nitrate against dermatophytes, yeasts and bacteria. Int J Dermatol. 2003 Sep;42 Suppl 1:11-7.|[3]Syed TA, Maibach HI. Butenafine hydrochloride: for the treatment of interdigital tinea pedis. Expert Opin Pharmacother. 2000 Mar;1 (3) :467-73.|[4]McNeely W, Spencer CM. Butenafine. Drugs. 1998 Mar;55 (3) :405-12; discussion 413.|[5]Butenafine