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YZ9

Y29 is a potent PFKFB3 inhibitor with an IC50 of 0.183 µM, and acts as a competitive inhibitor against Fru-6-P with a Ki value of 0.094 µM. Y29 exhibits antitumor effects against cervical cancer[1].

Product Specifications

CAS Number

6093-71-6

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/yz9.html

Concentration

10mM

Purity

99.20

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C1OC2=CC(O)=CC=C2C=C1C(OCC)=O

Molecular Formula

C12H10O5

Molecular Weight

234.21

Precautions

H302, H315, H319, H335

References & Citations

[1]Minsuh Seo, et al. Structure-based development of small molecule PFKFB3 inhibitors: a framework for potential cancer therapeutic agents targeting the Warburg effect. PLoS One. 2011;6 (9) :e24179.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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