GBRAP rabbit pAb

Gamma-aminobutyric acid A receptors [GABA (A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA (A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. [provided by RefSeq, Jul 2008],

Product Specifications

Background

UniProt

O95166

Swiss Prot

O95166

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human GBRAP AA range: 8-58

Target

GBRAP

Clonality

Polyclonal

Source

Rabbit

Applications

Concentration

1 mg/ml

Dilution

WB 1:500-2000

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Cytoplasmic vesicle, autophagosome membrane . Endomembrane system . Cytoplasm, cytoskeleton . Golgi apparatus membrane . Cytoplasmic vesicle . Largely associated with intracellular membrane structures including the Golgi apparatus and postsynaptic cisternae. Colocalizes with microtubules (By similarity) . Localizes also to discrete punctae along the ciliary axoneme (By similarity) . .