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GBRAP rabbit pAb

Gamma-aminobutyric acid A receptors [GABA (A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA (A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. [provided by RefSeq, Jul 2008],

Product Specifications

Background

Gamma-aminobutyric acid A receptors [GABA (A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA (A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. [provided by RefSeq, Jul 2008]

Gene ID

11337

UniProt

O95166

Cellular Locus

Cytoplasmic vesicle, autophagosome membrane. Endomembrane system. Cytoplasm, cytoskeleton. Golgi apparatus membrane. Cytoplasmic vesicle. Largely associated with intracellular membrane structures including the Golgi apparatus and postsynaptic cisternae. Colocalizes with microtubules (By similarity). Localizes also to discrete punctae along the ciliary axoneme (By similarity)..

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human GBRAP AA range: 8-58

Clonality

Polyclonal

Isotype

IgG

Source

Rabbit

Applications

WB

Validated Applications

WB

Stability

-20°C/1 year

Concentration

1 mg/mL

Dilution

WB 1: 500-2000

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES16226-1.pdf

Subcellular Location

Cytoplasmic vesicle, autophagosome membrane . Endomembrane system . Cytoplasm, cytoskeleton . Golgi apparatus membrane . Cytoplasmic vesicle . Largely associated with intracellular membrane structures including the Golgi apparatus and postsynaptic cisternae. Colocalizes with microtubules (By similarity) . Localizes also to discrete punctae along the ciliary axoneme (By similarity) . .

Gene ID (Human)

11337

SwissProt (Human)

O95166

Available Sizes

Curated Selection

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