BCN-HS-PEG2 (vcPABC-MMAE) 2

BCN-HS-PEG2 (vcPABC-MMAE) 2 is a drug-linker conjugate for ADC consists an ADC linker and a tubulin polymerization inhibitor MMAE (HY-15162) . BCN-HS-PEG2 (vcPABC-MMAE) 2 can be used in the synthesis of antibody-agent conjugates (ADCs) [1].

Product Specifications

CAS Number

[2126083-82-5]

UNSPSC

12352203

Target

Drug-Linker Conjugates for ADC; Microtubule/Tubulin

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bcn-hs-peg2-vcpabc-mmae-2.html

Purity

99.88

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(N1[C@](CCC1)([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C2=CC=CC=C2)O)=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC(C=C3)=CC=C3NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(OCCN(CCOC(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=O)C(NC4=CC=C(C=C4)COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N(C)[C@@H]([C@@H](C)CC)[C@H](OC)CC(N5[C@](CCC5)([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C6=CC=CC=C6)O)=O)=O)=O)=O)=O)=O)=O)=O)C(OCCOCCNS(NC(OC[C@H]7[C@]8([H])[C@@]7([H])CCC#CCC8)=O)(=O)=O)=O)=O)=O)=O)=O)=O)=O