Purified Anti-Human CD11c Antibody[3.9]
Product Specifications
Background
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4) . The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.
Abbreviation
CD11c
Gene ID
3687
UniProt
P20702
Host
Mouse
Reactivity
Human
Immunogen
Recombinant Human CD11c protein
Target
SLEB; Leukocyte adhesion receptor p150+; ITGAX; CD11C; SLEB6; CD11 antigen-like family member C; Integrin alpha-X; Leukocyte adhesion receptor p150+95; p150-95; CR4; integrin &alpha-X-X
Clonality
Monoclonal
Clone
3.9
Conjugation
Unconjugated
Applications
FCM
Field of Research
Signal Transduction; Immunology; Stem Cells
Purification
>98%, Protein A/G purified
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Product Datasheet
https://789.bio/ea/18cdeh
Product MSDS
https://789.bio/eb/00RVLC
Isotype
Mouse IgG1, κ
Available Sizes
Curated Selection
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