FH1
FH1 (NSC 12407) is a NQO2 inhibitor with hepatoprotective effects. FH1 enhances hepatocyte function and promotes differentiation of induced pluripotent stem (iPS) -derived hepatocytes to a more mature phenotype and maturation of well-differentiated hepatocyte-like cell (iHeps) cultures. FH1 protects against Acetaminophen -induced hepatotoxicity in both embryos and adult zebrafish[1][2][3].
Product Specifications
CAS Number
2719-05-3
Product Name Alternative
NSC 12407; BRD-K4477
UNSPSC
12352005
Hazard Statement
H400
Target
Quinone Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/FH1.html
Purity
99.17
Solubility
DMSO : 13 mg/mL (ultrasonic; warming)
Smiles
CC(NC1=CC=C(CC2=CC=C(NC(C)=O)C=C2)C=C1)=O
Molecular Formula
C17H18N2O2
Molecular Weight
282.34
Precautions
H400
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Frequently Asked Questions
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