Purified Anti-Human TCRVγ9 Antibody[B3]

The Vγ9 TCR is a variant of the TCR γ chain expressed on a subset of γ/δ T cells. Vγ9Vδ2 T lymphocytes, a major γ/δ T cell subset in humans, recognize phosphoantigens, certain tumor cells, and cells treated with aminobisphosphonates. This cell population displays cytolytic activity against various tumor cells. The γ/δ TCR is a heterodimeric TCR complex composed of covalently bound γ and δ chains involved in antigen recognition and the non-covalently associated monomorphic proteins CD3δ, γ, ε, and ζ chains. The B3 antibody reacts specifically with human TCR Vγ9 as designated by the Lefranc/Foster nomenclature system. Human TCR Vγ9 is also known as TCR Vγ2 under the Strauss, Quertermous nomenclature system. Several TCR γ and δ chain nomenclature systems exist. In order to consolidate the various nomenclature systems, we have created charts for corresponding names across some of the most popular naming methods