Pulchinenoside A
AA3 is a natural Pulsatilla saponin A that can improve synaptic plasticity in the hippocampus of adult mice and spatial memory in adult mice. It is also a non-competitive regulator of NMDA receptors.
Product Specifications
CAS Number
129724-84-1
Product Name Alternative
Anemoside A3
UNSPSC
12352005
Target
IGluR
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Pulchinenoside-A.html
Purity
98.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@]([H])(O[C@@H]2[C@@H](O)[C@@H](O)CO[C@@]2([H])O[C@@H]3[C@](CO)(C)[C@]4([H])CC[C@@]5(C)[C@]6(C)CC[C@@]7(C(O)=O)CC[C@@H](C(C)=C)[C@]7([H])[C@@]6([H])CC[C@]5([H])[C@@]4(C)CC3)O1
Molecular Formula
C41H66O12
Molecular Weight
750.96
References & Citations
[1]Ip FC et al. Anemoside A3 Enhances Cognition through the Regulation of Synaptic Function and Neuroprotection. Neuropsychopharmacology. 2015 Jul;40 (8) :1877-87.|[2]Zhang DM et al. Anemoside A3-induced relaxation in rat renal arteries: role of endothelium and Ca2+ channel inhibition. Planta Med. 2010 Nov;76 (16) :1814-9.|[3]Gao XD et al. Pulsatilloside A and anemoside A3 protect PC12 cells from apoptosis induced by sodium cyanide and glucose deprivation. Planta Med. 2003 Feb;69 (2) :171-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Available Sizes
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