P53-MDM2-IN-4

P53-MDM2-IN-4 (Example 4) is an inhibitor of p53-MDM2/X protein interaction, with a Ki value of 3.079 μM. p53-MDM2-IN-4 can be used in anti-tumor research[1].

Product Specifications

CAS Number

[350678-63-6]

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

E1/E2/E3 Enzyme; MDM-2/p53

Type

Reference compound

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/p53-mdm2-in-4.html

Purity

99.79

Solubility

DMSO : 5 mg/mL (ultrasonic)

Smiles

O=C(C1=C(O)C(N(C1C2=CC=C(F)C=C2)CCCN3C=CN=C3)=O)C4=CC=CC=C4

Molecular Formula

C23H20FN3O3

Molecular Weight

405.42

Precautions

H315, H319, H320

References & Citations

[1]Zhang W, et al. Pyrrylketone compound and application thereof as drug. CN102603717A. 2012-02-25.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature, keep dry and cool

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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