P53-MDM2-IN-4
P53-MDM2-IN-4 (Example 4) is an inhibitor of p53-MDM2/X protein interaction, with a Ki value of 3.079 μM. p53-MDM2-IN-4 can be used in anti-tumor research[1].
Product Specifications
CAS Number
[350678-63-6]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
E1/E2/E3 Enzyme; MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p53-mdm2-in-4.html
Purity
99.79
Solubility
DMSO : 5 mg/mL (ultrasonic)
Smiles
O=C(C1=C(O)C(N(C1C2=CC=C(F)C=C2)CCCN3C=CN=C3)=O)C4=CC=CC=C4
Molecular Formula
C23H20FN3O3
Molecular Weight
405.42
Precautions
H315, H319, H320
References & Citations
[1]Zhang W, et al. Pyrrylketone compound and application thereof as drug. CN102603717A. 2012-02-25.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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