2,6-Dichloro-9- (3,5-di-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl) -9H-purine
Selected Variant
HY-W550484
Size: 1 Each
2,6-Dichloro-9- (3,5-di-O-benzoyl-2-deoxy-2-fluoro-D-arabinofuranosyl) -9H-purine arabinoriboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
329187-80-6
UNSPSC
12352005
Hazard Statement
H302-H315-H320-H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-6-dichloro-9-3-5-di-o-benzoyl-2-deoxy-2-fluoro-d-arabinofuranosyl-9h-purine.html
Solubility
10 mM in DMSO
Smiles
ClC1=C(N=C2)C(N2[C@@H]3O[C@H](COC(C4=CC=CC=C4)=O)[C@@H](OC(C5=CC=CC=C5)=O)[C@@H]3F)=NC(Cl)=N1
Molecular Formula
C24H17Cl2FN4O5
Molecular Weight
531.32
Precautions
P264-P270-P330
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Price
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