Miltirone
Miltirone is an orally active natural compound found in the root of Salvia miltiorrhiza. Miltirone is a central benzodiazepine receptor partial agonist, with an IC50 of 0.3 μM. Miltirone induces ROS - and-p53 dependent apoptosis. Miltirone inhibits carboxylesterase 2 (CES2; Ki = 0.04 μM) and SARS-CoV main protease (Mpro) [1][2][3][4].
Product Specifications
CAS Number
27210-57-7
Product Name Alternative
Rosmariquinone
UNSPSC
12352005
Target
Apoptosis; Carboxylesterase (CES) ; GABA Receptor; SARS-CoV
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/miltirone.html
Concentration
10mM
Purity
99.74
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1C(C(C)C)=CC2=C(C3=C(C=C2)C(C)(C)CCC3)C1=O
Molecular Formula
C19H22O2
Molecular Weight
282.38
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
CES2
Available Sizes
Frequently Asked Questions
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