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(S,R,S)-AHPC-PEG5-COOH

Product Specifications

Product Name Alternative

VH032-PEG5-COOH; VHL Ligand-Linker Conjugates 16; E3 Ligase Ligand-Linker Conjugates 58

UNSPSC Description

(S,R,S)-AHPC-PEG5-COOH (VH032-PEG5-COOH) is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and 5-unit PEG linker used in PROTAC technology[1].

Target Antigen

E3 Ligase Ligand-Linker Conjugates

Type

Reference compound

Related Pathways

PROTAC

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/vhl-ligand-linker-conjugates-16.html

Purity

99.88

Solubility

DMSO : 200 mg/mL (ultrasonic)|H2O : ≥ 100 mg/mL

Smiles

O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(CCOCCOCCOCCOCCOCCC(O)=O)=O)=O)C[C@H](O)C3

Molecular Weight

750.90

References & Citations

[1]Chi JJ, et al. A novel strategy to block mitotic progression for targeted therapy. EBioMedicine. 2019 Oct 25. pii: S2352-3964(19)30677-2.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-130271/S-R-S-AHPC-PEG5-COOH-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-130271/S-R-S-AHPC-PEG5-COOH-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2172820-14-1

Available Sizes

Curated Selection

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