EBNA1-IN-SC7

EBNA1-IN-SC7 (compound SC7) is a selective Epstein-Barr nuclear antigen 1 (EBNA1) inhibitor that interferes with EBNA1-DNA binding activity with an IC50 value of 23 μM. EBNA1-IN-SC7 is used in EBV (Epstein-Barr virus) -related cancer research[1].

Product Specifications

CAS Number

[324022-08-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

EBV

Type

Reference compound

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ebna1-in-sc7.html

Purity

99.92

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

CC(N(C1=CC=C(OC(C)=O)C(Br)=C1)S(=O)(C2=CC=C3C=CC=CC3=C2)=O)=O

Molecular Formula

C20H16BrNO5S

Molecular Weight

462.32

Precautions

H302, H315, H319, H335

References & Citations

[1]Lijun Jiang, et al. EBNA1-targeted inhibitors: Novel approaches for the treatment of Epstein-Barr virus-associated cancers. Theranostics. 2018 Oct 22;8 (19) :5307-5319.|[2]Ning Li, et al. Discovery of selective inhibitors against EBNA1 via high throughput in silico virtual screening. PLoS One. 2010 Apr 12;5 (4) :e10126.