LFNG Recombinant Rabbit Monoclonal Antibody [JE66-62]

Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity).

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Abbreviation

LFNG

Swiss Prot

Q8NES3 Human, O09010 Mouse

Cellular Locus

Golgi apparatus membrane.

Host

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthetic peptide within Human LFNG aa 330-379 / 379.

Isotype

IgG

Clone

JE66-62

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, FC

Positive Control

Hela cell lysate, K-562 cell lysate, HL-60 cell lysate, MCF7 cell lysate, HT-29 cell lysate, C2C12 cell lysate, PC-12 cell lysate, mouse testis tissue lysate, HUVEC, MCF7, K-562.