LFNG Recombinant Rabbit Monoclonal Antibody [JE66-62]
Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity).
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Abbreviation
LFNG
Swiss Prot
Q8NES3 Human, O09010 Mouse
Cellular Locus
Golgi apparatus membrane.
Host
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide within Human LFNG aa 330-379 / 379.
Isotype
IgG
Clone
JE66-62
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, FC
Positive Control
Concentration
1mg/mL
Dilution
WB: 1:1,000 ;IF-Cell: 1:500 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 42 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
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