AZ99
AZ99 (compound 7) is a potent ABCG2 inhibitor. AZ99 inhibits ABCG2-mediated transport of estrone-3-sulfate (E1S) into proteoliposomes and ABCG2 ATPase activity[1].
Product Specifications
UNSPSC
12352211
Target
BCRP
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/az99.html
Smiles
O=C1N[C@@H](CC2=CC=CC=C2)C(N3[C@@H](CC(C)C)C4=C(C5=CC=C(OC6CCCC6)C=C5N4)C[C@H]31)=O
Molecular Formula
C30H35N3O3
Molecular Weight
485.62
References & Citations
[1]Yu Q, et al. Modulation of ABCG2 Transporter Activity by Ko143 Derivatives. ACS Chem Biol. 2024 Oct 24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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