VD2173 epimer-1
VD2173 epimer-1 is a racemic mixture of VD2173 (HY-145263) [1].
Product Specifications
UNSPSC
12352005
Target
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vd2173-epimer-1.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
O=C1N[C@H](C(NC(C(C2=NC3=CC=CC=C3S2)=O)CCCNC(N)=N)=O)CCCCNC(C[C@H](NC(C)=O)C(N[C@H]1CC(C)C)=O)=O
Molecular Formula
C31H45N9O6S
Molecular Weight
671.81
References & Citations
[1]Damalanka VC, et, al. Macrocyclic Inhibitors of HGF-Activating Serine Proteases Overcome Resistance to Receptor Tyrosine Kinase Inhibitors and Block Lung Cancer Progression. J Med Chem. 2021 Dec 23;64 (24) :18158-18174.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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