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VD2173 epimer-1

VD2173 epimer-1 is a racemic mixture of VD2173 (HY-145263) [1].

Product Specifications

UNSPSC

12352005

Target

Ser/Thr Protease

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/vd2173-epimer-1.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

O=C1N[C@H](C(NC(C(C2=NC3=CC=CC=C3S2)=O)CCCNC(N)=N)=O)CCCCNC(C[C@H](NC(C)=O)C(N[C@H]1CC(C)C)=O)=O

Molecular Formula

C31H45N9O6S

Molecular Weight

671.81

References & Citations

[1]Damalanka VC, et, al. Macrocyclic Inhibitors of HGF-Activating Serine Proteases Overcome Resistance to Receptor Tyrosine Kinase Inhibitors and Block Lung Cancer Progression. J Med Chem. 2021 Dec 23;64 (24) :18158-18174.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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