CPTH2-Alkyne
CPTH2-Alkyne is a cell active analog of CPTH2. CPTH2-Alkyne specifically accumulates in nucleoli and locates in nuclear periphery and in cytoplasma. CPTH2-Alkyne inhibits N-acetyltransferase 10 (NAT10). CPTH2-Alkyne is used in study of nuclear architecture and application in laminopathy[1].
Product Specifications
CAS Number
1613116-16-7
UNSPSC
12352005
Target
Histone Acetyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cpth2-alkyne.html
Purity
99.9
Solubility
10 mM in DMSO
Smiles
ClC1=CC=C(C2=CSC(N(CC#C)/N=C3CCCC\3)=N2)C=C1
Molecular Formula
C17H16ClN3S
Molecular Weight
329.85
References & Citations
[1]Larrieu D, et al., Chemical inhibition of NAT10 corrects defects of laminopathic cells. Science. 2014 May 2;344 (6183) :527-32.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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