Obefazimod

Obefazimod (ABX464) is a potent anti-HIV agent. Obefazimod inhibits HIV-1 replication in stimulated peripheral blood mononuclear cells (PBMCs) with an IC50 ranging between 0.1 μM and 0.5 μM.

Product Specifications

CAS Number

[1258453-75-6]

Product Name Alternative

ABX464

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ABX464.html

Purity

99.85

Solubility

DMSO : ≥ 100 mg/mL

Smiles

FC(F)(F)OC1=CC=C(NC2=NC3=C(Cl)C=CC=C3C=C2)C=C1

Molecular Formula

C16H10ClF3N2O

Molecular Weight

338.71

Precautions

H302, H315, H319, H335

References & Citations

[1]Campos N, et al. Long lasting control of viral rebound with a new drug ABX464 targeting Rev-mediated viral RNA biogenesis. Retrovirology. 2015 Apr 9;12:30.