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Nitrendipine (Standard)

Nitrendipine (Standard) is the analytical standard of Nitrendipine. This product is intended for research and analytical applications. Nitrendipine (BAY-E-5009) is an orally active analog of Nifedipine (HY-B0284) and dihydropyridine calcium channel blocker. Nitrendipine induces Apoptosis. Nitrendipine has antihypertensive effects. Nitrendipine blocks alcohol and Morphine withdrawal symptoms. Nitrendipine reduces right ventricular hypertrophy and pulmonary vascular changes induced by intermittent hypoxia. Nitrendipine has anticancer effects on neuroblastoma[1][2][3][4][5][6][7][8][9][10][11].

Product Specifications

CAS Number

39562-70-4

Product Name Alternative

BAY-E-5009 (Standard)

UNSPSC

12352005

Hazard Statement

H312-H332-H362

Target

Apoptosis; Calcium Channel; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Cancer; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/nitrendipine-standard.html

Smiles

O=C(C1=C(C)NC(C)=C(C(OC)=O)C1C2=CC=CC([N+]([O-])=O)=C2)OCC

Molecular Formula

C18H20N2O6

Molecular Weight

360.36

Precautions

P260-P261-P263-P264-P270-P271-P280-P302+P352-P304+P340-P362+P364-P501

References & Citations

[1]Bellemann, P., et al., [3H]-Nitrendipine, a potent calcium antagonist, binds with high affinity to cardiac membranes. Arzneimittelforschung, 1981. 31 (12) : p. 2064-7.|[2]S Kazda, et al. Diuretic effect of nitrendipine contributes to its antihypertensive efficacy: a review. J Cardiovasc Pharmacol. 1988;12 Suppl 4:S1-5.|[3]He-Hui Xie, et al. Synergism of atenolol and nitrendipine on hemodynamic amelioration and organ protection in hypertensive rats. J Hypertens. 2005 Jan;23 (1) :193-201.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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