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1-Cyclohexyl-3-dodecyl urea

1-Cyclohexyl-3-dodecyl urea (CDU; N-Cyclohexyl-N-dodecyl urea; NCND) is a highly selective soluble epoxide hydrolase (sEH) inhibitor. 1-Cyclohexyl-3-dodecyl urea (CDU; N-Cyclohexyl-N-dodecyl urea; NCND) increases epoxyeicosatrienoic acids (EETs) levels and lowers blood pressure in angiotensin II (Ang II) hypertension[1].

Product Specifications

CAS Number

[402939-18-8]

Product Name Alternative

CDU; N-Cyclohexyl-N-dodecyl urea; NCND

UNSPSC

12352211

Hazard Statement

H302, H413

Target

Epoxide Hydrolase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/1-cyclohexyl-3-dodecyl-urea.html

Purity

98.0

Solubility

Ethanol : 16.67 mg/mL (ultrasonic)

Smiles

O=C(NCCCCCCCCCCCC)NC1CCCCC1

Molecular Formula

C19H38N2O

Molecular Weight

310.52

Precautions

H302, H413

References & Citations

[1]Imig JD, et al. Soluble epoxide hydrolase inhibition lowers arterial blood pressure in angiotensin II hypertension.Hypertension. 2002 Feb;39 (2 Pt 2) :690-4.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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