Lactitol (monohydrate)

Lactitol monohydrate (D-Lactitol monohydrate) is a sugar analog of lactulose. Lactitol monohydrate acts as a prebiotic, fermented by intestinal flora, promoting the growth of beneficial bacteria (such as Lactobacillus and Bifidobacterium), inhibiting pathogenic bacteria, increasing volatile fatty acid production, and reducing ammonia levels. Lactitol monohydrate can be used as an alternative sweetener. Lactitol monohydrate can be also used in research on constipation and hepatic encephalopathy[1][2][3].

Product Specifications

CAS Number

[81025-04-9]

Product Name Alternative

D-Lactitol (monohydrate)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/Lactitol-monohydrate.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 120 mg/mL (ultrasonic)

Smiles

OC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O[C@H]1[C@@H]([C@H]([C@H]([C@@H](CO)O1)O)O)O)O)O.[H]O[H]

Molecular Formula

C12H26O12

Molecular Weight

362.33

Precautions

H302, H315, H319, H335

References & Citations

[1]Yamamoto Y, et al. Continuous combined intake of polydextrose and lactitol stimulates cecal fermentation and salivary IgA secretion in rats. J Oral Sci. 2017;59 (4) :603-610.|[2]Piva A, et al. Effect of lactitol, lactic acid bacteria, or their combinations (synbiotic) on intestinal proteolysis in vitro, and on feed efficiency in weaned pigs. Canadian journal of animal science, 2005, 85 (3) : 345-353.|[3]Jang JH, et al. Lactitol Alleviates Loperamide-Induced Constipation in Sprague Dawley Rats by Regulating Serotonin, Short-Chain Fatty Acids, and Gut Microbiota. Foods. 2024 Jul 3;13 (13) :2128.