Angiotensinogen (1-14), human

Angiotensinogen (1-14), human is a fragment of the renin substrate angiotensinogen. Angiotensinogen is naturally occurring substrate for renin and a precursor for all angiotensin peptides[1][2].

Product Specifications

CAS Number

[104180-23-6]

UNSPSC

12352209

Target

Endogenous Metabolite

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Angiotensinogen__1-14_,_human.html

Purity

99.40

Solubility

H2O : ≥ 6.25 mg/mL

Smiles

OC(C=C1)=CC=C1C[C@H](NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](N)CC(O)=O)=O)=O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC2=CN=CN2)C(N3[C@@H](CCC3)C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N[C@H](C(O)=O)CC(N)=O)=O)CC4=CN=CN4)=O)=O)=O)=O)CC5=CN=CN5)=O)CC6=CC=CC=C6)=O)=O)=O)=O

Molecular Formula

C83H122N24O19

Molecular Weight

1760.01

References & Citations

[1]Lu H, et al. Structure and functions of angiotensinogen. Hypertens Res. 2016 Jul;39 (7) :492-500.|[2]Burton J, et al. The amino-acid residues on the C-terminal side of the cleavage site of angiotensinogeninfluence the species specificity of reaction with renin. iochim Biophys Acta. 1988 Jan 4;952 (1) :8-12.