SLB1122168 (formic)

SLB1122168 formic is a potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM[1].

Product Specifications

UNSPSC

12352005

Target

LPL Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/slb1122168-formic.html

Concentration

10mM

Purity

99.91

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCCCCCCCC1=CC=C2C(OC(NC[C@@H]3CNCC3)=N2)=C1.OC=O

Molecular Formula

C23H37N3O3

Molecular Weight

403.56

References & Citations

[1]Ariel L Burgio, et al. 2-Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2) . J Med Chem. 2023 Apr 27;66 (8) :5873-5891.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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