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FABP1-IN-1

FABP1-IN-1 (44) is a selective FABP1 inhibitor, with an IC50 of 4.46 μM. FABP1-IN-1 (44) can be used for the research of NASH[1].

Product Specifications

CAS Number

3048021-44-6

UNSPSC

12352005

Target

FABP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/fabp1-in-1.html

Purity

99.95

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC(C2=CC=CC(OCC3CC3)=C2)=CC(C(O)=O)=C1)C4=CC(OC5=CC=CC=C5)=CC=C4

Molecular Formula

C30H25NO5

Molecular Weight

479.52

References & Citations

[1]Ya Chen, et al. Design, synthesis, and biological evaluation of first-in-class FABP1 inhibitors for the treatment of NASH. Eur J Med Chem. 2024 Apr 15:270:116358.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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