FABP1-IN-1
FABP1-IN-1 (44) is a selective FABP1 inhibitor, with an IC50 of 4.46 μM. FABP1-IN-1 (44) can be used for the research of NASH[1].
Product Specifications
CAS Number
3048021-44-6
UNSPSC
12352005
Target
FABP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/fabp1-in-1.html
Purity
99.95
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC(C2=CC=CC(OCC3CC3)=C2)=CC(C(O)=O)=C1)C4=CC(OC5=CC=CC=C5)=CC=C4
Molecular Formula
C30H25NO5
Molecular Weight
479.52
References & Citations
[1]Ya Chen, et al. Design, synthesis, and biological evaluation of first-in-class FABP1 inhibitors for the treatment of NASH. Eur J Med Chem. 2024 Apr 15:270:116358.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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