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DEPTOR-IN-1

DEPTOR-IN-1 is a novel putative DEPTOR inhibitor with a Kd value of 9.3 μM.

Product Specifications

CAS Number

2615911-12-9

UNSPSC

12352005

Target

MTOR

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/deptor-in-1.html

Purity

99.09

Solubility

DMSO : 4 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C2=CC=C3OCN(CC3=C2OC(C4=CC(Cl)=C(C=C4)Cl)=C1O)CC5=CC(F)=CC=C5

Molecular Formula

C24H16Cl2FNO4

Molecular Weight

472.29

References & Citations

[1]Hou Y, et al. Design, Synthesis, and Biological Evaluation of Icaritin Derivatives as Novel Putative DEPTOR Inhibitors for Multiple Myeloma Treatment. J Med Chem. 2021 Oct 28;64 (20) :14942-14954.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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