Trimyristin--d15

Trimyristin--d15 is the deuterium labeled Trimyristin. Trimyristin, an active molluscicidal component of Myristica fragrans Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC50s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively[1].

Product Specifications

CAS Number

[1219804-94-0]

UNSPSC

12352211

Target

Cholinesterase (ChE) ; Endogenous Metabolite; Isotope-Labeled Compounds; Phosphatase

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling; Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Solubility

10 mM in DMSO

Smiles

[2H]C([2H])([2H])C([2H])([2H])CCCCCCCCCCCC(OC(COC(CCCCCCCCCCCC([2H])([2H])C([2H])([2H])[2H])=O)COC(CCCCCCCCCCCC([2H])([2H])C([2H])([2H])[2H])=O)=O

Molecular Formula

C45H71D15O6

Molecular Weight

738.25

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Jaiswal P, et al. Enzyme Inhibition by Molluscicidal Components of Myristica fragrans Houtt. in the NervousTissue of Snail Lymnaea acuminata. Enzyme Res. 2010;2010:478746.