Trimyristin--d15
Product Specifications
UNSPSC Description
Trimyristin--d15 is the deuterium labeled Trimyristin. Trimyristin, an active molluscicidal component of Myristica fragrans Houtt, significantly inhibits acetylcholinesterase (AChE), acid and alkaline phosphatase (ACP/ALP) activities in the nervous tissue of Lymnaea acuminata. IC50s of Trimyristin against AChE, ACP, and ALP are 0.11, 0.16 and 0.18 mM, respectively[1].
Target Antigen
Cholinesterase (ChE); Endogenous Metabolite; Isotope-Labeled Compounds; Phosphatase
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease;Neuronal Signaling;Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])C([2H])([2H])CCCCCCCCCCCC(OC(COC(CCCCCCCCCCCC([2H])([2H])C([2H])([2H])[2H])=O)COC(CCCCCCCCCCCC([2H])([2H])C([2H])([2H])[2H])=O)=O
Molecular Weight
738.25
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Jaiswal P, et al. Enzyme Inhibition by Molluscicidal Components of Myristica fragrans Houtt. in the NervousTissue of Snail Lymnaea acuminata. Enzyme Res. 2010;2010:478746.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
CAS Number
1219804-94-0
Available Sizes
Curated Selection
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