PCI-27483
PCI-27483 is a FVIIa/tissue factor inhibitor, with antitumour effects.
Product Specifications
CAS Number
[871266-63-6]
UNSPSC
12352005
Target
Factor VIIa
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/PCI-27483.html
Purity
99.10
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
O=C(O)C[C@@H](C(O)=O)NC(CC1=CC(C2=CC(S(=O)(N)=O)=CC=C2O)=C(O)C(C3=NC4=CC=C(C(N)=N)C=C4N3)=C1)=O
Molecular Formula
C26H24N6O9S
Molecular Weight
596.57
References & Citations
[1]Gómez-Outes A, et al. New parenteral anticoagulants in development. Ther Adv Cardiovasc Dis. 2011 Feb;5 (1) :33-59.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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