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PCI-27483

PCI-27483 is a FVIIa/tissue factor inhibitor, with antitumour effects.

Product Specifications

CAS Number

871266-63-6

UNSPSC

12352005

Target

Factor VIIa

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/PCI-27483.html

Purity

99.10

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=C(O)C[C@@H](C(O)=O)NC(CC1=CC(C2=CC(S(=O)(N)=O)=CC=C2O)=C(O)C(C3=NC4=CC=C(C(N)=N)C=C4N3)=C1)=O

Molecular Formula

C26H24N6O9S

Molecular Weight

596.57

References & Citations

[1]Gómez-Outes A, et al. New parenteral anticoagulants in development. Ther Adv Cardiovasc Dis. 2011 Feb;5 (1) :33-59.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Available Sizes

Frequently Asked Questions

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