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Arundic Acid

Product Specifications

UNSPSC Description

Arundic acid (ONO-2506) is an astrocyte-modulating agent, which delays the expansion of cerebral infarcts by modulating the activation of astrocytes through inhibition of S-100β synthesis. Arundic acid has the potential for stroke and Alzheimer’s disease research[1][2][3].

Target Antigen

Others

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/arundic-acid.html

Purity

98.0

Solubility

DMSO : 150 mg/mL (ultrasonic)

Smiles

CCCCCC[C@H](C(O)=O)CCC

Molecular Weight

186.29

References & Citations

[1]Tomoyuki Hasegawa, et al. Process Development of ONO-2506:  A Therapeutic Agent for Stroke and Alzheimer's Disease. Org. Process Res. Dev.200372168-171.|[2]Kato H, et al. Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTPneurotoxicity in mice. Brain Res. 2004 Dec 24;1030(1):66-73.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-107661/Arundic-Acid-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-107661/Arundic-Acid-SDS-MedChemExpress.pdf

Clinical Information

Phase 3

CAS Number

185517-21-9

Available Sizes

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