Pterostilbene

Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium[1]. Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties[1][4]. Pterostilbene blocks ROS production[3], also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide[4].

Product Specifications

CAS Number

[537-42-8]

UNSPSC

12352005

Hazard Statement

H318, H411

Target

Autophagy

Type

Natural Products

Related Pathways

Autophagy

Applications

Cancer-programmed cell death

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Pterostilbene.html

Purity

99.90

Solubility

DMSO : 110 mg/mL (ultrasonic)

Smiles

OC1=CC=C(/C=C/C2=CC(OC)=CC(OC)=C2)C=C1

Molecular Formula

C16H16O3

Molecular Weight

256.30

Precautions

H318, H411

References & Citations

[1]McCormack D, et al. A review of pterostilbene antioxidant activity and disease modification. Oxid Med Cell Longev. 2013;2013:575482.|[2]Hong Bin W, et al. Pterostilbene (3',5'-dimethoxy-resveratrol) exerts potent antitumor effects in HeLa human cervical cancer cells via disruption of mitochondrial membrane potential, apoptosis induction and targeting m-TOR/PI3K/Akt signalling pathway. J BUON. 2018 Sep-Oct;23 (5) :1384-1389.|[3]Perecko T, et al. The effects of pterostilbene on neutrophil activity in experimental model of arthritis. Biomed Res Int. 2013;2013:106041.|[4]Acharya JD, et al. Protective effect of Pterostilbene against free radical mediated oxidative damage. BMC Complement Altern Med. 2013 Sep 26;13:238.