Cefoperazone

Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity[1].

Product Specifications

CAS Number

[62893-19-0]

UNSPSC

12352005

Hazard Statement

H317, H334

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cefoperazone.html

Purity

99.82

Solubility

DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL

Smiles

O=C(C(N12)=C(CSC3=NN=NN3C)CS[C@]2([H])[C@H](NC([C@H](NC(N4C(C(N(CC)CC4)=O)=O)=O)C5=CC=C(O)C=C5)=O)C1=O)O

Molecular Formula

C25H27N9O8S2

Molecular Weight

645.67

Precautions

H317, H334

References & Citations

[1]N Matsubara, et al. In vitro antibacterial activity of cefoperazone (T-1551), a new semisynthetic cephalosporin. Antimicrob Agents Chemother. 1979 Dec;16 (6) :731-5.|[2]Pedro H.Di Rocco, et al. Aerosol treatment with cefoperazone or gentamicin protects granulocytopenic mice from acute Pseudomonas aeruginosa pneumonia. European Journal of Pharmaceutical Sciences Volume 1, Issue 6, June 1994, Pages 285-289.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

β-lactam

Citation 01

Carbohydr Polym. 2024 Jan 1:323:121379.|J Antibiot (Tokyo) . 2023 Apr;76 (4) :225-235.|Mol Med. 2024 Nov 6;30 (1) :203.|Toxicol Appl Pharmacol. 2023 Apr 1:464:116447.|Carbohydr Polym. 2024 Jan 1:323:121379.