Cefoperazone
Cefoperazone, a semisynthetic cephalosporin, has a broad spectrum of antibacterial activity[1].
Product Specifications
CAS Number
62893-19-0
UNSPSC
12352005
Hazard Statement
H317, H334
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cefoperazone.html
Purity
99.82
Solubility
DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL
Smiles
O=C(C(N12)=C(CSC3=NN=NN3C)CS[C@]2([H])[C@H](NC([C@H](NC(N4C(C(N(CC)CC4)=O)=O)=O)C5=CC=C(O)C=C5)=O)C1=O)O
Molecular Formula
C25H27N9O8S2
Molecular Weight
645.67
Precautions
H317, H334
References & Citations
[1]N Matsubara, et al. In vitro antibacterial activity of cefoperazone (T-1551), a new semisynthetic cephalosporin. Antimicrob Agents Chemother. 1979 Dec;16 (6) :731-5.|[2]Pedro H.Di Rocco, et al. Aerosol treatment with cefoperazone or gentamicin protects granulocytopenic mice from acute Pseudomonas aeruginosa pneumonia. European Journal of Pharmaceutical Sciences Volume 1, Issue 6, June 1994, Pages 285-289.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β-lactam
Citation 01
Carbohydr Polym. 2024 Jan 1:323:121379.|J Antibiot (Tokyo) . 2023 Apr;76 (4) :225-235.|Mol Med. 2024 Nov 6;30 (1) :203.|Toxicol Appl Pharmacol. 2023 Apr 1:464:116447.|Carbohydr Polym. 2024 Jan 1:323:121379.
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