Recombinant Human BDNF

Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophic factor family. BDNF binds with high affinity to the TrkB kinase receptor, alongside other neurotrophic factors such as NGF, NT-3, and NT-4. It also binds to LNGFR (low-affinity nerve growth factor receptor, also known as p75). BDNF promotes the survival, growth, and differentiation of neurons. It is a major regulatory factor for synaptic transmission and plasticity in the adult central nervous system. The expression levels of BDNF are altered in neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease. Recombinant Human/Murine/Rat BDNF is expressed by E.coli, and is produced with raw materials of pharmaceutical applicable level. The host protein residue, nucleic acid residue and common pathogens are strictly controlled, and the production and quality management procedures of the product comply with GMP regulations to ensure the traceability of the production process and all raw materials.