Recombinant Mouse IL-33 Protein (Trx Tag)
Product Specifications
Background
Interleukin 33 (IL-33), also known as DVS27 or NF-HEV (Nuclear Factor from High Endothelial Venules), is a pro-inflammatory protein and a chromatin-associated cytokine of the IL-1 family with high sequence and structural similarity to IL-1 and IL-18. IL-33 protein is expressed highly and rather selectively by high endothelial venule endothelial cells (HEVECs) in human tonsils, Peyer's patches, and lymph nodes. IL-33 protein has transcriptional regulatory properties, and the researches suggested that IL-33 is a dual-function protein that might act both as a cytokine and as an intracellular nuclear factor. As a type 2 cytokines, IL-33 protein also play a pivotal role in helminthic infection and allergic disorders.
Abbreviation
IL-33
Synonyms
DVS; NF-HEV and IL- 1F; Interleukin-1 family member; C9orf; C9orf26; DVS27; Interleukin-1 family member 11; NF-HEV and IL- 1F11; NKHEV; IL33; Interleukin-33; IL-33; Interleukin 33; IL1F11; NFEHEV; NF-HEV
UniProt
Q8BVZ5
Accession Number
Q8BVZ5
Expression System
E.coli
Tag
N-Trx
Sequence
Gln109-Ile266
Field of Research
Cancer; Immunology; Signal Transduction
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method
Purity
> 95% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/orooxd
Product MSDS
https://789.bio/eb/Z9CdSK
Calculated Molecular Weight
37.4 kDa
Observed Molecular Weight
37 kDa
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Species
Mouse
Available Sizes
Curated Selection
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