AKT Kinase Inhibitor
AKT Kinase Inhibitor is an Akt kinase inhibitor with anti-tumor activity[1].
Product Specifications
CAS Number
[842148-40-7]
UNSPSC
12352005
Hazard Statement
H301
Target
Akt
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/AKT-Kinase-Inhibitor.html
Purity
99.92
Solubility
DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OCC#CC1=NC=C(C2=C1N=C(N2CC)C3=NON=C3N)OCCCN
Molecular Formula
C16H19N7O3
Molecular Weight
357.37
Precautions
H301
References & Citations
[1]Saverio Alberti, et al. Use of trop-2 as predictive marker of response to anti-tumor therapy based on inhibitors of cd9, akt and molecules of the tetraspanin signalling network. WO2013171777A2.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Citation 01
Biofactors. 2025 May-Jun;51 (3) :e70023.|Cell Commun Signal. 2022 Mar 19;20 (1) :35.|Cell Rep. 2023 May 23;42 (6) :112547.|Cell Stem Cell. 2023 Apr 6;30 (4) :450-459.e9.|Inflammation. 2021 Jun;44 (3) :890-898.|Int J Biol Sci. 2024 Apr 29;20 (7) :2748-2762.|J Cancer. 2021 May 5;12 (13) :3809-3818.|Life Sci. 2019 Aug 15:231:116554.|Mediators Inflamm. 2020 Jun 24;2020:3621261.|Oxid Med Cell Longev. 2021 Mar 19:2021:5595376.|Pharmacol Res. 2024 May 18:107218.|Phytother Res. 2022 Apr;36 (4) :1724-1735.|Research Square Preprint. 2020 Dec.|Research Square Preprint. 2023 May 26.|Small. 2023 Apr;19 (16) :e2207194.|Cell Death Dis. 2024 Nov 9;15 (11) :809.
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