Rac1 Inhibitor W56 (TFA)
Rac1 Inhibitor W56 TFA is a peptide containing residues 45-60 of Rac1. Rac1 Inhibitor W56 TFA inhibits Rac1 interaction with guanine nucleotide exchange factors TrioN, GEF-H1, and Tiam[1].
Product Specifications
UNSPSC
12352209
Target
Ras
Type
Peptides
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rac1-inhibitor-w56-tfa.html
Purity
99.92
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
OC(CNC([C@H](C)NC([C@H]([C@H](O)C)NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CC(C)C)NC(CNC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@H]1N(CCC1)C([C@H](CCCCN)NC(CNC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@@H](N)CCSC)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O.[x]
Molecular Formula
C74H117N19O23S.xC2HF3O2
Molecular Weight
1671.93 (free acid)
References & Citations
[1]Gao Y, Xing J, et al. Trp (56) of rac1 specifies interaction with a subset of guanine nucleotide exchange factors [published correction appears in J Biol Chem. 2005 Jan 14;280 (2) :1704]. J Biol Chem. 2001;276 (50) :47530-47541.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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