GDC-4379
Product Specifications
UNSPSC Description
GDC-4379 is a JAK1 inhibitor that can be used for the research of asthma[1].
Target Antigen
JAK
Type
Reference compound
Related Pathways
Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/gdc-4379.html
Solubility
DMSO : 31.25 mg/mL (ultrasonic)
Smiles
O=C(C1=C2N=CC=CN2N=C1)NC3=CN(CC(N(C)C)=O)N=C3C4=CC(Cl)=CC=C4OC(F)F
Molecular Weight
489.86
References & Citations
[1]Stumpf A, et, al. Efficient, Protecting Group Free Kilogram-Scale Synthesis of the JAK1 Inhibitor GDC-4379. Org. Process Res. Dev. 2021, 25, 11, 2537-2550.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139837/GDC-4379-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139837/GDC-4379-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2252277-73-7
Available Sizes
Curated Selection
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