GDC-4379
GDC-4379 is a JAK1 inhibitor that can be used for the research of asthma[1].
Product Specifications
CAS Number
2252277-73-7
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/gdc-4379.html
Purity
98.23
Solubility
DMSO : 31.25 mg/mL (ultrasonic)
Smiles
O=C(C1=C2N=CC=CN2N=C1)NC3=CN(CC(N(C)C)=O)N=C3C4=CC(Cl)=CC=C4OC(F)F
Molecular Formula
C21H18ClF2N7O3
Molecular Weight
489.86
References & Citations
[1]Stumpf A, et, al. Efficient, Protecting Group Free Kilogram-Scale Synthesis of the JAK1 Inhibitor GDC-4379. Org. Process Res. Dev. 2021, 25, 11, 2537-2550.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb1596616 100 µL
NFKB p65 Recombinant Rabbit mAb, Biotin conjugated
Sign In for Pricing
View Details 
243009-ML405 100 µL
ACAA2 (Acetyl-Coenzyme A Acyltransferase 2, DSAEC, FLJ35992, FLJ95265) (MaxLight 405) discontinued
Sign In for Pricing
View Details