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CP-868388 (free base)

CP-868388 free base is a potent, selective and orally active PPARα agonist with a Ki value of 10.8 nM. CP-868388 free base has little or no affinity for PPARβ (Ki of 3.47 μM) and PPARγ. CP-868388 free base has hypolipidemic and anti-inflammatory actions[1].

Product Specifications

CAS Number

702681-67-2

Product Name Alternative

Adonitol; Adonite

UNSPSC

12352005

Hazard Statement

H301, H400, H410

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cp-868388-free-base.html

Purity

99.66

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(N1C[C@H](C2=CC=CC(OC(C)(C(O)=O)C)=C2)CCC1)OCC3=CC=C(C(C)C)C=C3

Molecular Formula

C26H33NO5

Molecular Weight

439.54

Precautions

H301, H400, H410

References & Citations

[1]Christopher D Kane, et al. Molecular characterization of novel and selective peroxisome proliferator-activated receptor alpha agonists with robust hypolipidemic activity in vivo. Mol Pharmacol. 2009 Feb;75 (2) :296-306.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PPARα; PPARγ

Available Sizes

Frequently Asked Questions

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