RO5263397
RO5263397 is a potent, selective, and orally available TAAR1 agonist, with EC50s of 17 and 35 nM for human TAAR1 and rat TAAR1, respectively. RO5263397 regulates wakefulness and EEG spectral composition. Antidepressant-like effect[1][2][3].
Product Specifications
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Trace Amine-associated Receptor (TAAR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ro5263397.html
Purity
98.87
Solubility
DMSO : 260 mg/mL (ultrasonic)
Smiles
CC1=C([C@@H]2N=C(N)OC2)C=CC=C1F
Molecular Formula
C10H11FN2O
Molecular Weight
194.21
Precautions
H302, H315, H319
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-108015/RO5263397-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-108015/RO5263397-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
CAS Number
[1357266-05-7]
Available Sizes
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