IST5-002
IST5-002, a potent Stat5a/b inhibitor, selectively inhibits transcriptional activity of Stat5a/b (IC50s: 1.5 μM for Stat5a, 3.5 μM for Stat5b) . IST5-002 inducs cell apoptotic and death of prostate cancer cells and chronic myeloid leukemia (CML) cells. IST5-002 can be used in the research of prostate cancer and chronic myeloid leukemia (CML) [1].
Product Specifications
CAS Number
13484-66-7
Product Name Alternative
N6-Benzyladenosine-5'-phosphate
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H332, H335
Target
Apoptosis; STAT
Type
Reference compound
Related Pathways
Apoptosis; JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ist5-002.html
Concentration
10mM
Purity
99.83
Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 125 mg/mL (ultrasonic)
Smiles
O=P(O)(OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C(N=CN=C32)NCC4=CC=CC=C4)O1)O)O)O
Molecular Formula
C17H20N5O7P
Molecular Weight
437.34
Precautions
H302, H315, H319, H332, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
STAT5
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Rabbit Polyclonal GTP binding protein era homolog Antibody
Recombinant Mycobacterium sp. Probable cytosol aminopeptidase (pepA), partial
