IST5-002
IST5-002, a potent Stat5a/b inhibitor, selectively inhibits transcriptional activity of Stat5a/b (IC50s: 1.5 μM for Stat5a, 3.5 μM for Stat5b) . IST5-002 inducs cell apoptotic and death of prostate cancer cells and chronic myeloid leukemia (CML) cells. IST5-002 can be used in the research of prostate cancer and chronic myeloid leukemia (CML) [1].
Product Specifications
CAS Number
[13484-66-7]
Product Name Alternative
N6-Benzyladenosine-5'-phosphate
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H332, H335
Target
Apoptosis; STAT
Type
Reference compound
Related Pathways
Apoptosis; JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ist5-002.html
Concentration
10mM
Purity
99.83
Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 125 mg/mL (ultrasonic)
Smiles
O=P(O)(OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C(N=CN=C32)NCC4=CC=CC=C4)O1)O)O)O
Molecular Formula
C17H20N5O7P
Molecular Weight
437.34
Precautions
H302, H315, H319, H332, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
STAT5
Available Sizes
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