2,4-Dihydroxybenzaldehyde

2,4-Dihydroxybenzaldehyde is an endogenous metabolite. 2,4-Dihydroxybenzaldehyde is a pharmaceutical intermediate that can be used to synthesize various Schiff base compounds. 2,4-Dihydroxybenzaldehyde exhibits significant anti angiogenic, anti-inflammatory, and analgesic activities. 2,4-Dihydroxybenzaldehyde reduces the production of NO and ROS by inhibiting the expression of iNOS and COX-2. 2,4-Dihydroxybenzaldehyde is commonly used in the study of inflammatory conditions[1][2].

Product Specifications

CAS Number

[95-01-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335, H402

Target

COX; Drug Intermediate; Endogenous Metabolite; NO Synthase; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/2-4-dihydroxybenzaldehyde.html

Purity

99.93

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=CC1=CC=C(O)C=C1O

Molecular Formula

C7H6O3

Molecular Weight

138.12

Precautions

H302, H315, H319, H335, H402

References & Citations

[1]Murtaza S, et al. Synthesis, biological activities and docking studies of novel 2, 4-dihydroxybenzaldehyde based Schiff base. Medicinal Chemistry Research, 2016, 25 (12) : 2860-2871.|[2]Jung H J, et al. Evaluation on pharmacological activities of 2, 4-dihydroxybenzaldehyde. Biomolecules & Therapeutics, 2009, 17 (3) : 263-269.